Redox-Active Sensing by Bacterial DksA Transcription Factors Is Determined by Cysteine and Zinc Content

The four-cysteine zinc finger motif of the bacterial RNA polymerase regulator DksA is essential for protein structure, canonical control of the stringent response to nutritional limitation, and thiol-based sensing of oxidative and nitrosative stress. This interdependent relationship has limited our...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Crawford, Matthew A., Tapscott, Timothy, Fitzsimmons, Liam F., Liu, Lin, Reyes, Aníbal M., Libby, Stephen J., Trujillo, Madia, Fang, Ferric C., Radi, Rafael, Vázquez-Torres, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850274/
https://ncbi.nlm.nih.gov/pubmed/27094335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02161-15
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