DksA–DnaJ redox interactions provide a signal for the activation of bacterial RNA polymerase

RNA polymerase is the only known protein partner of the transcriptional regulator DksA. Herein, we demonstrate that the chaperone DnaJ establishes direct, redox-based interactions with oxidized DksA. Cysteine residues in the zinc finger of DksA become oxidized in Salmonella exposed to low concentrat...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kim, Ju-Sim, Liu, Lin, Fitzsimmons, Liam F., Wang, Yang, Crawford, Matthew A., Mastrogiovanni, Mauricio, Trujillo, Madia, Till, James Karl A., Radi, Rafael, Dai, Shaodong, Vázquez-Torres, Andrés
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294903/
https://ncbi.nlm.nih.gov/pubmed/30429329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813572115
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