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DksA regulates RNA polymerase in Escherichia coli through a network of interactions in the secondary channel that includes Sequence Insertion 1

Sensing and responding to nutritional status is a major challenge for microbial life. In Escherichia coli, the global response to amino acid starvation is orchestrated by guanosine-3′,5′-bisdiphosphate and the transcription factor DksA. DksA alters transcription by binding to RNA polymerase and allo...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Parshin, Andrey, Shiver, Anthony L., Lee, Jookyung, Ozerova, Maria, Schneidman-Duhovny, Dina, Gross, Carol A., Borukhov, Sergei
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687573/
https://ncbi.nlm.nih.gov/pubmed/26604313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521365112
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