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Polycistronic trypanosome mRNAs are a target for the exosome
Eukaryotic cells have several mRNA quality control checkpoints to avoid the production of aberrant proteins. Intron-containing mRNAs are actively degraded by the nuclear exosome, prevented from nuclear exit and, if these systems fail, degraded by the cytoplasmic NMD machinery. Trypanosomes have only...
Enregistré dans:
| Publié dans: | Mol Biochem Parasitol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier/North-Holland Biomedical Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850246/ https://ncbi.nlm.nih.gov/pubmed/26946399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2016.02.009 |
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