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Mammalian polycistronic mRNAs and disease

Our understanding of gene expression has come far since the “one-gene one-polypeptide” hypothesis proposed by Beadle and Tatum. This review addresses the gradual recognition that a growing number of polycistronic genes, originally discovered in viruses, are being identified within the mammalian geno...

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Détails bibliographiques
Publié dans:Trends Genet
Auteurs principaux: Karginov, Timofey A., Hejazi Pastor, Daniel Parviz, Semler, Bert L., Gomez, Christopher M.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5285393/
https://ncbi.nlm.nih.gov/pubmed/28012572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2016.11.007
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