Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition

Selenium supplement has been shown in clinical trials to reduce the risk of different cancers including lung carcinoma. Previous studies reported that the antiproliferative and pro-apoptotic activities of methylseleninic acid (MSA) in cancer cells could be mediated by inhibition of the PI3K pathway....

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Detaylı Bibliyografya
Yayımlandı:Pharmacol Res
Asıl Yazarlar: Tarrado-Castellarnau, Míriam, Cortés, Roldán, Zanuy, Miriam, Tarragó-Celada, Josep, Polat, Ibrahim H., Hill, Richard, Fan, Teresa W., Link, Wolfgang, Cascante, Marta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850087/
https://ncbi.nlm.nih.gov/pubmed/26375988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2015.09.009
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