Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition

Selenium supplement has been shown in clinical trials to reduce the risk of different cancers including lung carcinoma. Previous studies reported that the antiproliferative and pro-apoptotic activities of methylseleninic acid (MSA) in cancer cells could be mediated by inhibition of the PI3K pathway....

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Tarrado-Castellarnau, Míriam, Cortés, Roldán, Zanuy, Miriam, Tarragó-Celada, Josep, Polat, Ibrahim H., Hill, Richard, Fan, Teresa W., Link, Wolfgang, Cascante, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850087/
https://ncbi.nlm.nih.gov/pubmed/26375988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2015.09.009
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