Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition

Selenium supplement has been shown in clinical trials to reduce the risk of different cancers including lung carcinoma. Previous studies reported that the antiproliferative and pro-apoptotic activities of methylseleninic acid (MSA) in cancer cells could be mediated by inhibition of the PI3K pathway....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmacol Res
Egile Nagusiak: Tarrado-Castellarnau, Míriam, Cortés, Roldán, Zanuy, Miriam, Tarragó-Celada, Josep, Polat, Ibrahim H., Hill, Richard, Fan, Teresa W., Link, Wolfgang, Cascante, Marta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850087/
https://ncbi.nlm.nih.gov/pubmed/26375988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2015.09.009
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