Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-γ in experimental biliary atresia

The etiology and pathogenesis of bile duct obstruction in children with biliary atresia are largely unknown. We have previously reported that, despite phenotypic heterogeneity, genomic signatures of livers from patients display a proinflammatory phenotype. Here, we address the hypothesis that produc...

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Hauptverfasser: Shivakumar, Pranavkumar, Campbell, Kathleen M., Sabla, Gregg E., Miethke, Alexander, Tiao, Greg, McNeal, Monica M., Ward, Richard L., Bezerra, Jorge A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC484981/
https://ncbi.nlm.nih.gov/pubmed/15286798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421153
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