Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-γ in experimental biliary atresia

The etiology and pathogenesis of bile duct obstruction in children with biliary atresia are largely unknown. We have previously reported that, despite phenotypic heterogeneity, genomic signatures of livers from patients display a proinflammatory phenotype. Here, we address the hypothesis that produc...

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Detalhes bibliográficos
Main Authors: Shivakumar, Pranavkumar, Campbell, Kathleen M., Sabla, Gregg E., Miethke, Alexander, Tiao, Greg, McNeal, Monica M., Ward, Richard L., Bezerra, Jorge A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC484981/
https://ncbi.nlm.nih.gov/pubmed/15286798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421153
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