Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-γ in experimental biliary atresia

The etiology and pathogenesis of bile duct obstruction in children with biliary atresia are largely unknown. We have previously reported that, despite phenotypic heterogeneity, genomic signatures of livers from patients display a proinflammatory phenotype. Here, we address the hypothesis that produc...

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Autores principales: Shivakumar, Pranavkumar, Campbell, Kathleen M., Sabla, Gregg E., Miethke, Alexander, Tiao, Greg, McNeal, Monica M., Ward, Richard L., Bezerra, Jorge A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2004
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC484981/
https://ncbi.nlm.nih.gov/pubmed/15286798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421153
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