Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-γ in experimental biliary atresia

The etiology and pathogenesis of bile duct obstruction in children with biliary atresia are largely unknown. We have previously reported that, despite phenotypic heterogeneity, genomic signatures of livers from patients display a proinflammatory phenotype. Here, we address the hypothesis that produc...

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Autori principali: Shivakumar, Pranavkumar, Campbell, Kathleen M., Sabla, Gregg E., Miethke, Alexander, Tiao, Greg, McNeal, Monica M., Ward, Richard L., Bezerra, Jorge A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC484981/
https://ncbi.nlm.nih.gov/pubmed/15286798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421153
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