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Central and peripheral actions of somatostatin on the growth hormone–IGF-I axis
Somatostatin (SRIF) analogs provide safe and effective therapy for acromegaly. In a proportion of patients, however, SRIF analogs may lead to discordant growth hormone (GH) and IGF-I suppression, which suggests a more complex mechanism than attributable to inhibition of GH release alone. To elucidat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC484973/ https://ncbi.nlm.nih.gov/pubmed/15286801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419933 |
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