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Pyridoxal Phosphate Inhibits Pituitary Cell Proliferation And Hormone Secretion
Pyridoxal phosphate (PLP), a bio-active form of pyridoxine, (10-1000 μM) dose-dependently inhibited cell proliferation in rat pituitary MMQ and GH3 cells, and in mouse AtT-20 cells. After 4 days, MMQ cell numbers were reduced by up to 81%, GH3 cell numbers were reduced by up to 64% (p<0.05) and A...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1513048/ https://ncbi.nlm.nih.gov/pubmed/16690808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2005-1219 |
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