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EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas

Cushing disease is a condition in which the pituitary gland releases excessive adrenocorticotropic hormone (ACTH) as a result of an adenoma arising from the ACTH-secreting cells in the anterior pituitary. ACTH-secreting pituitary adenomas lead to hypercortisolemia and cause significant morbidity and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fukuoka, Hidenori, Cooper, Odelia, Ben-Shlomo, Anat, Mamelak, Adam, Ren, Song-Guang, Bruyette, Dave, Melmed, Shlomo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226010/
https://ncbi.nlm.nih.gov/pubmed/22105169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60417
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