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Constitutive Somatostatin Receptor Subtype-3 Signaling Suppresses Growth Hormone Synthesis

Somatostatin signals through somatostatin receptor subtypes (SSTR) 2 and 5 to attenuate GH secretion. Although expressed in normal pituitary glands and in GH-secreting pituitary tumors, SSTR3 function was unclear, and we have now determined the role of SSTR3 in somatotroph function. Stable rat pitui...

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Autors principals: Eigler, Tamar, Ben-Shlomo, Anat, Zhou, Cuiqi, Khalafi, Ramtin, Ren, Song-Guang, Melmed, Shlomo
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968402/
https://ncbi.nlm.nih.gov/pubmed/24606125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1327
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