The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen

Mechanical injury to the skin results in activation of the complement component C3 and release of the anaphylatoxin C3a. C3a binds to a seven-transmembrane G protein–coupled receptor, C3aR. We used C3aR(–/–) mice to examine the role of C3a in a mouse model of allergic inflammation induced by epicuta...

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Xehetasun bibliografikoak
Egile Nagusiak: Kawamoto, Seiji, Yalcindag, Ali, Laouini, Dhafer, Brodeur, Scott, Bryce, Paul, Lu, Bao, Humbles, Alison A., Oettgen, Hans, Gerard, Craig, Geha, Raif S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2004
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC484971/
https://ncbi.nlm.nih.gov/pubmed/15286806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419082
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