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Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy

BACKGROUND: Trimetazidine, as an anti-ischemic and antioxidant agent, has been demonstrated to have many cardioprotective effects. However, whether early administration of trimetazidine has an effect on diabetic cardiomyopathy and the mechanisms underlying the effect have not yet been elucidated. ME...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Transl Med
Päätekijät: Zhang, Lei, Ding, Wen-yuan, Wang, Zhi-hao, Tang, Meng-xiong, Wang, Feng, Li, Ya, Zhong, Ming, Zhang, Yun, Zhang, Wei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848862/
https://ncbi.nlm.nih.gov/pubmed/27121077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0849-1
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