Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy

BACKGROUND: Trimetazidine, as an anti-ischemic and antioxidant agent, has been demonstrated to have many cardioprotective effects. However, whether early administration of trimetazidine has an effect on diabetic cardiomyopathy and the mechanisms underlying the effect have not yet been elucidated. ME...

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Detaylı Bibliyografya
Yayımlandı:J Transl Med
Asıl Yazarlar: Zhang, Lei, Ding, Wen-yuan, Wang, Zhi-hao, Tang, Meng-xiong, Wang, Feng, Li, Ya, Zhong, Ming, Zhang, Yun, Zhang, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848862/
https://ncbi.nlm.nih.gov/pubmed/27121077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0849-1
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