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Identification of Small‐Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia‐1 (Mcl‐1)

Protein–protein interactions (PPIs) control many cellular processes in cancer and tumour growth. Of significant interest is the role PPIs play in regulating apoptosis. The overexpression of the antiapoptosis regulating Bcl‐2 family of proteins is commonly observed in several cancers, leading to resi...

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Detaylı Bibliyografya
Yayımlandı:ChemMedChem
Asıl Yazarlar: Beekman, Andrew M., O'Connell, Maria A., Howell, Lesley A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848766/
https://ncbi.nlm.nih.gov/pubmed/26616140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500488
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