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ADAM10 Cell Surface Expression but Not Activity Is Critical for Staphylococcus aureus α-Hemolysin-Mediated Activation of the NLRP3 Inflammasome in Human Monocytes

The Staphylococcus aureus toxin, α-hemolysin, is an important and well-studied virulence factor in staphylococcal infection. It is a soluble monomeric protein that, once secreted by the bacterium, forms a heptameric pore in the membrane of a broad range of host cell types. Hemolysin was recently dis...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Toxins (Basel)
Päätekijät: Ezekwe, Ejiofor A.D., Weng, Chengyu, Duncan, Joseph A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848622/
https://ncbi.nlm.nih.gov/pubmed/27043625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8040095
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