Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

Community Acquired Methicillin Resistant Staphylococcus aureus (CA-MRSA) causes severe necrotizing infections of the skin, soft tissues, and lungs. Staphylococcal α-hemolysin is an essential virulence factor in mouse models of CA-MRSA necrotizing pneumonia. S. aureus α-hemolysin has long been known...

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Main Authors: Craven, Robin R., Gao, Xi, Allen, Irving C., Gris, Denis, Wardenburg, Juliane Bubeck, McElvania-TeKippe, Erin, Ting, Jenny P., Duncan, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758589/
https://ncbi.nlm.nih.gov/pubmed/19826485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007446
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