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Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus α-hemolysin–mediated cellular injury

Staphylococcus aureus α-hemolysin (Hla), a potent cytotoxin, plays an important role in the pathogenesis of staphylococcal diseases, including those caused by methicillin-resistant epidemic strains. Hla is secreted as a water-soluble monomer that undergoes a series of conformational changes to gener...

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Detalhes bibliográficos
Main Authors: Wilke, Georgia A., Wardenburg, Juliane Bubeck
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922128/
https://ncbi.nlm.nih.gov/pubmed/20624979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001815107
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