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A Staphylococcus aureus Pore-Forming Toxin Subverts the Activity of ADAM10 to Cause Lethal Infection

Staphylococcus aureus is a major cause of human disease, responsible for half a million infections and approximately 20,000 deaths per year in the United States alone (1,2). This pathogen secretes α-hemolysin, a pore-forming cytotoxin that contributes to the pathogenesis of pneumonia (3–5). α-hemoly...

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Detalhes bibliográficos
Main Authors: Inoshima, Ichiro, Inoshima, Naoko, Wilke, Georgia, Powers, Michael, Frank, Karen, Wang, Yang, Wardenburg, Juliane Bubeck
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192248/
https://ncbi.nlm.nih.gov/pubmed/21926978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2451
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