Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration

Photoreceptors are the most numerous and metabolically demanding cells in the retina. Their primary nutrient source is the choriocapillaris, and both the choriocapillaris and photoreceptors require trophic and functional support from retinal pigment epithelium (RPE) cells. Defects in RPE, photorecep...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Kurihara, Toshihide, Westenskow, Peter D, Gantner, Marin L, Usui, Yoshihiko, Schultz, Andrew, Bravo, Stephen, Aguilar, Edith, Wittgrove, Carli, Friedlander, Mollie SH, Paris, Liliana P, Chew, Emily, Siuzdak, Gary, Friedlander, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848091/
https://ncbi.nlm.nih.gov/pubmed/26978795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14319
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