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Targeted deletion of Vegfa in adult mice induces vision loss

Current therapies directed at controlling vascular abnormalities in cancers and neovascular eye diseases target VEGF and can slow the progression of these diseases. While the critical role of VEGF in development has been well described, the function of locally synthesized VEGF in the adult eye is in...

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Détails bibliographiques
Auteurs principaux: Kurihara, Toshihide, Westenskow, Peter D., Bravo, Stephen, Aguilar, Edith, Friedlander, Martin
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484459/
https://ncbi.nlm.nih.gov/pubmed/23093773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65157
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