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Validating the disruption of proliferating cell nuclear antigen interactions in the development of targeted cancer therapeutics

Human DNA replication and repair is a highly coordinated process involving the specifically timed actions of numerous proteins and enzymes. Many of these proteins require interaction with proliferating cell nuclear antigen (PCNA) for activation within the process. The interdomain connector loop (IDC...

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Publicat a:Cancer Biol Ther
Autors principals: Smith, Shanna J., Hickey, Robert J., Malkas, Linda H.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847981/
https://ncbi.nlm.nih.gov/pubmed/26889573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1139247
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