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Validating the disruption of proliferating cell nuclear antigen interactions in the development of targeted cancer therapeutics

Human DNA replication and repair is a highly coordinated process involving the specifically timed actions of numerous proteins and enzymes. Many of these proteins require interaction with proliferating cell nuclear antigen (PCNA) for activation within the process. The interdomain connector loop (IDC...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Smith, Shanna J., Hickey, Robert J., Malkas, Linda H.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847981/
https://ncbi.nlm.nih.gov/pubmed/26889573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1139247
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