A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer

Proliferating cell nuclear antigen (PCNA) is a highly conserved protein necessary for proper component loading during the DNA replication and repair process. Proteins make a connection within the interdomain connector loop of PCNA, and much of the regulation is a result of the inherent competition f...

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Publicado no:Mol Pharmacol
Main Authors: Smith, Shanna J., Gu, Long, Phipps, Elizabeth A., Dobrolecki, Lacey E., Mabrey, Karla S., Gulley, Pattie, Dillehay, Kelsey L., Dong, Zhongyun, Fields, Gregg B., Chen, Yun-Ru, Ann, David, Hickey, Robert J., Malkas, Linda H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293449/
https://ncbi.nlm.nih.gov/pubmed/25480843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093211
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