Generation of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle

Blastocyst complementation (BC) systems have enabled in vivo generation of organs from allogeneic pluripotent cells, compensating for an empty germ cell niche in gene knockout (KO) animals. Here, we succeeded in producing chimeric beef cattle (Wagyu) by transferring allogenic germ cells into ovaries...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ideta, Atsushi, Yamashita, Shiro, Seki-Soma, Marie, Yamaguchi, Ryosaku, Chiba, Shiori, Komaki, Haruna, Ito, Tetsuya, Konishi, Masato, Aoyagi, Yoshito, Sendai, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846992/
https://ncbi.nlm.nih.gov/pubmed/27117862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24983
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