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Inducible Sterilization of Zebrafish by Disruption of Primordial Germ Cell Migration
During zebrafish development, a gradient of stromal-derived factor 1a (Sdf1a) provides the directional cue that guides the migration of the primordial germ cells (PGCs) to the gonadal tissue. Here we describe a method to produce large numbers of infertile fish by inducing ubiquitous expression of Sd...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694954/ https://ncbi.nlm.nih.gov/pubmed/23826390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068455 |
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