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Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis
In a previous study we reported the role of potent bisindole-PBD conjugate as an inclusion in the arsenal of breast cancer therapeutics. In breast cancer cell proliferation, PI3K/AKT/mTOR pathway plays a crucial role by prosurvival mechanism that inhibits programmed cell death. Here, 2 breast cancer...
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| Publicado no: | Cancer Biol Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846128/ https://ncbi.nlm.nih.gov/pubmed/26192233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1071731 |
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