A novel bisindole-PBD conjugate causes DNA damage induced apoptosis via inhibition of DNA repair pathway

DNA damage response (DDR) that includes cell cycle check points, DNA repair, apoptosis, and senescence is intimately linked with cancer. It shields an organism against cancer development when genomic integrity fails. DNA repair pathways protect the cells from tumor progression caused as a result of...

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Detaylı Bibliyografya
Asıl Yazarlar: Sarma, Pranjal, Ramaiah, M Janaki, Kamal, Ahmed, Bhadra, Utpal, Bhadra, Manika Pal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2014
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130725/
https://ncbi.nlm.nih.gov/pubmed/25010292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29705
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