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A novel bisindole-PBD conjugate causes DNA damage induced apoptosis via inhibition of DNA repair pathway

DNA damage response (DDR) that includes cell cycle check points, DNA repair, apoptosis, and senescence is intimately linked with cancer. It shields an organism against cancer development when genomic integrity fails. DNA repair pathways protect the cells from tumor progression caused as a result of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sarma, Pranjal, Ramaiah, M Janaki, Kamal, Ahmed, Bhadra, Utpal, Bhadra, Manika Pal
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130725/
https://ncbi.nlm.nih.gov/pubmed/25010292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29705
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