Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer

Tumor microenvironment play role in angiogenesis and carcinogenesis. Etoposide, a known topoisomerase II inhibitor induces DNA damage resulting in cell cycle arrest. We developed a novel Etoposide analogue, Quinazolino-4β-amidopodophyllotoxin (C-10) that show better efficacy in regulating cell proli...

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Foilsithe in:PLoS One
Main Authors: Srinivas, Chatla, Ramaiah, M. Janaki, Lavanya, A., Yerramsetty, Suresh, Kavi Kishor, P. B, Basha, Shaik Anver, Kamal, Ahmed, Bhadra, Utpal, Bhadra, Manika-Pal
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638343/
https://ncbi.nlm.nih.gov/pubmed/26551008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142006
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