Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia

A-kinase anchor protein 12 (AKAP12) is a regulator of protein kinase A and protein kinase C signaling, acting downstream of RAS. Epigenetic silencing of AKAP12 has been demonstrated in different cancer entities and this has been linked to the process of tumorigenesis. Here, we used quantitative high...

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Dettagli Bibliografici
Pubblicato in:Epigenetics
Autori principali: Wilhelm, Thomas, Lipka, Daniel B., Witte, Tania, Wierzbinska, Justyna A., Fluhr, Silvia, Helf, Monika, Mücke, Oliver, Claus, Rainer, Konermann, Carolin, Nöllke, Peter, Niemeyer, Charlotte M., Flotho, Christian, Plass, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
Brief Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846096/
https://ncbi.nlm.nih.gov/pubmed/26891149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1145327
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