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Plk1 inhibition enhances the efficacy of gemcitabine in human pancreatic cancer
Gemcitabine is the standard-of-care for chemotherapy in patients with pancreatic adenocarcinoma and it can directly incorporate into DNA or inhibit ribonucleotide reductase to prevent DNA replication and, thus, tumor cell growth. Most pancreatic tumors, however, develop resistance to gemcitabine. Po...
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| Publié dans: | Cell Cycle |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845940/ https://ncbi.nlm.nih.gov/pubmed/26890815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1148838 |
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