A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

The inactive X chromosome (Xi) serves as a model to understand gene silencing on a global scale. Here, we perform “identification of direct RNA interacting proteins” (iDRiP) to isolate a comprehensive protein interactome for Xist, an RNA required for Xi silencing. We discover multiple classes of int...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Minajigi, Anand, Froberg, John, Wei, Chunyao, Sunwoo, Hongjae, Kesner, Barry, Colognori, David, Lessing, Derek, Payer, Bernhard, Boukhali, Myriam, Haas, Wilhelm, Lee, Jeannie T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845908/
https://ncbi.nlm.nih.gov/pubmed/26089354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab2276
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