A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

The inactive X chromosome (Xi) serves as a model to understand gene silencing on a global scale. Here, we perform “identification of direct RNA interacting proteins” (iDRiP) to isolate a comprehensive protein interactome for Xist, an RNA required for Xi silencing. We discover multiple classes of int...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Science
Hoofdauteurs: Minajigi, Anand, Froberg, John, Wei, Chunyao, Sunwoo, Hongjae, Kesner, Barry, Colognori, David, Lessing, Derek, Payer, Bernhard, Boukhali, Myriam, Haas, Wilhelm, Lee, Jeannie T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845908/
https://ncbi.nlm.nih.gov/pubmed/26089354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab2276
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items