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Inflammasome-mediated glucocorticoid resistance: The receptor rheostat

In primary acute lymphoblastic leukemia cells exhibiting de novo resistance to glucocorticoids, we recently discovered decreased promoter methylation of caspase 1 (CASP1) and NLR family, pyrin domain containing 3 (NLRP3), which resulted in increased transcription, constitutive NALP3 (NACHT, LRR and...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Paugh, Steven W., Bonten, Erik J., Evans, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845245/
https://ncbi.nlm.nih.gov/pubmed/27308575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1065947
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