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Rapamycin: A rheostat for CD8(+) T-cell-mediated tumor therapy

Vaccines that generate Ag-specific CD8(+) T-cell responses of appropriate quality, magnitude and duration are highly desirable. The ability of mTOR to regulate CD8(+) T-cell functional differentiation must be exploited for clinical benefit. In a recent paper, we report that varying the regimen of ra...

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Detalhes bibliográficos
Main Authors: Srivastava, Rupesh K., Utley, Adam, Shrikant, Protul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494641/
https://ncbi.nlm.nih.gov/pubmed/23170275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20663
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