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Transcription factor Foxo1 represses T-bet mediated effector functions and promotes memory CD8(+) T cell differentiation

The evolutionary conserved Foxo transcription factors are important regulators of quiescence and longevity. Although, Foxo1 is known to be important in regulating CD8(+) T cell trafficking and homeostasis, its role in functional differentiation of antigen stimulated CD8(+) T cells is unclear. Herein...

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Detalhes bibliográficos
Main Authors: Rao, Rajesh R., Li, Qingsheng, Gubbels Bupp, Melanie R., Shrikant, Protul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314246/
https://ncbi.nlm.nih.gov/pubmed/22425248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.01.015
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