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Uncoupling protein 2 regulates metabolic reprogramming and fate of antigen-stimulated CD8+ T cells

Adoptive cell therapy (ACT) employing ex vivo-generated tumor antigen-specific CD8+ T cells shows tumor efficacy when the transferred cells possess both effector and memory functions. New strategies based on understanding of mechanisms that balance CD8+ T cell differentiation toward effector and mem...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Chaudhuri, Leena, Srivastava, Rupesh K., Kos, Ferdynand, Shrikant, Protul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919150/
https://ncbi.nlm.nih.gov/pubmed/27271549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1851-4
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