Development of Aortic Valve Disease in Familial Hypercholesterolemic Swine: Implications for Elucidating Disease Etiology

BACKGROUND: Familial hypercholesterolemia (FH) is a prevalent hereditary disease associated with increased atherosclerosis and calcific aortic valve disease (CAVD). However, in both FH and non‐FH individuals, the role of hypercholesterolemia in the development of CAVD is poorly understood. This stud...

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Foilsithe in:J Am Heart Assoc
Main Authors: Porras, Ana M., Shanmuganayagam, Dhanansayan, Meudt, Jennifer J., Krueger, Christian G., Hacker, Timothy A., Rahko, Peter S., Reed, Jess D., Masters, Kristyn S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2015
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845146/
https://ncbi.nlm.nih.gov/pubmed/26508741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002254
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