Development of Aortic Valve Disease in Familial Hypercholesterolemic Swine: Implications for Elucidating Disease Etiology

BACKGROUND: Familial hypercholesterolemia (FH) is a prevalent hereditary disease associated with increased atherosclerosis and calcific aortic valve disease (CAVD). However, in both FH and non‐FH individuals, the role of hypercholesterolemia in the development of CAVD is poorly understood. This stud...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Porras, Ana M., Shanmuganayagam, Dhanansayan, Meudt, Jennifer J., Krueger, Christian G., Hacker, Timothy A., Rahko, Peter S., Reed, Jess D., Masters, Kristyn S.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845146/
https://ncbi.nlm.nih.gov/pubmed/26508741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002254
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