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Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification

BACKGROUND: Extracellular matrix (ECM) disarray is found in calcific aortic valvular disease (CAVD), yet much remains to be learned about the role of individual ECM components in valvular interstitial cell (VIC) function and dysfunction. Previous clinical analyses have shown that calcification is as...

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Detalhes bibliográficos
Main Authors: Rodriguez, Karien J, Piechura, Laura M, Porras, Ana M, Masters, Kristyn S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946110/
https://ncbi.nlm.nih.gov/pubmed/24581344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-14-29
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