Development of Aortic Valve Disease in Familial Hypercholesterolemic Swine: Implications for Elucidating Disease Etiology

BACKGROUND: Familial hypercholesterolemia (FH) is a prevalent hereditary disease associated with increased atherosclerosis and calcific aortic valve disease (CAVD). However, in both FH and non‐FH individuals, the role of hypercholesterolemia in the development of CAVD is poorly understood. This stud...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Porras, Ana M., Shanmuganayagam, Dhanansayan, Meudt, Jennifer J., Krueger, Christian G., Hacker, Timothy A., Rahko, Peter S., Reed, Jess D., Masters, Kristyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845146/
https://ncbi.nlm.nih.gov/pubmed/26508741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002254
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