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Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan
Cellular senescence, a stress-induced irreversible growth arrest often characterized by p16(Ink4a) expression and a distinctive secretory phenotype, prevents the proliferation of preneoplastic cells and has beneficial roles in tissue remodelling during embryogenesis and wound healing. Senescent cell...
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| 發表在: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845101/ https://ncbi.nlm.nih.gov/pubmed/26840489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16932 |
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