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Structural correlates of affinity in fetal versus adult endplate nicotinic receptors

Adult-type nicotinic acetylcholine receptors (AChRs) mediate signalling at mature neuromuscular junctions and fetal-type AChRs are necessary for proper synapse development. Each AChR has two neurotransmitter binding sites located at the interface of a principal and a complementary subunit. Although...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nayak, Tapan Kumar, Chakraborty, Srirupa, Zheng, Wenjun, Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845029/
https://ncbi.nlm.nih.gov/pubmed/27101778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11352
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