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The multidrug resistance pump ABCB1 is a substrate for the ubiquitin ligase NEDD4-1
The ATP Binding Cassette transporter ABCB1 can export the neurotoxic peptide β-amyloid from endothelial cells that line the blood-brain barrier (BBB). This has the potential to lower cerebral levels of β-amyloid, but ABCB1 expression in the BBB appears to be progressively reduced in patients with Al...
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| Publicado no: | Mol Membr Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844833/ https://ncbi.nlm.nih.gov/pubmed/26006083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09687688.2015.1023378 |
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