Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A(2) activity

Peroxiredoxin 6 (Prdx6) is a unique 1-Cys member of the peroxiredoxin family with both GSH peroxidase and phospholipase A(2) (PLA(2)) activities. It is highly expressed in the lung where it plays an important role in antioxidant defense and lung surfactant metabolism. Glutathionylation of Prdx6 medi...

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Xehetasun bibliografikoak
Argitaratua izan da:Free Radic Biol Med
Egile Nagusiak: Zhou, Suiping, Sorokina, Elena M., Harper, Sandra, Li, Haitao, Ralat, Luis, Dodia, Chandra, Speicher, David W., Feinstein, Sheldon I., Fisher, Aron B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844822/
https://ncbi.nlm.nih.gov/pubmed/26891882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.02.012
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