Novel Autophosphorylation Sites of Src Family Kinases Regulate Kinase Activity and SH2 Domain Binding Capacity

Src family tyrosine kinases (SFKs) are critical players in normal and aberrant biological processes. While phosphorylation importantly-regulates SFKs at two known tyrosines, large-scale phosphoproteomics have revealed four additional tyrosines commonly-phosphorylated in SFKs. We found these novel ty...

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Pubblicato in:FEBS Lett
Autori principali: Weir, Marion E., Mann, Jacqueline E., Corwin, Thomas, Fulton, Zachary W., Hao, Jennifer M., Maniscalco, Jeanine F., Kenney, Marie C., Roque, Kristal M. Roman, Chapdelaine, Elizabeth F., Stelzl, Ulrich, Deming, Paula B., Ballif, Bryan A., Hinkle, Karen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844773/
https://ncbi.nlm.nih.gov/pubmed/27001024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12144
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